Seleniso Laos Edition Instructions

Selinesol belongs to the class of selective nuclear export inhibitors. It inhibits the growth of cancer cells by affecting the transport of important proteins in the nucleus. Specifically, it prevents the transport of CRM1 protein between the nucleus and cytoplasm, which is critical for intracellular signaling. By inhibiting CRM1, selinesol disrupts the normal functions of cancer cells, thereby slowing their proliferation. CurrentlySelinesol is mainly used to treat adult multiple myeloma (including relapsed or refractory multiple myeloma, referred to asRRMM) and diffuse large B-cell lymphoma.

1. Drug name

Selinexor

2. Manufacturer

Lao Big Bear Pharmaceutical Co., Ltd., Lao Lucius Pharmaceutical Co., Ltd.

3. Usage and dosage

1. Recommended dose for multiple myeloma: combined with bortezomib and dexamethasone, 100 mg orally on the 1st day of the week. In combination with dexamethasone, take 80 mg orally on days 1 and 3 of each week.

2. Recommended dose for lymphoma: 60 mg orally on the 1st and 3rd day of each week.

3. It is recommended to take the medicine at the same time on each medication day. The specific time is determined by the doctor.

4. Take the medicine with a full glass of water. Make sure to swallow the medicine completely without crushing or chewing.

5. If you vomit soon after taking it, you should not take it again and wait until the next dose time.

4. Precautions

1. Before using selinesol, your doctor should be informed in detail of your personal medical history and other drugs you are taking to avoid potential drug interactions.

2. Pregnant and lactating women should consult a doctor before use. It is generally recommended to use effective contraception during treatment and for 1 week after the last dose and to avoid breastfeeding.

3. Selinisol may cause some side effects, such as fatigue, anemia, nausea, vomiting, loss of appetite, diarrhea, weight loss, etc. If serious side effects occur, seek medical attention immediately.

7. Specifications and Prices

The specifications of Laos Luxiu version of Seleniso are20mg*32 tablets, a box sells for about more than 2,000. The size of the Daxiong version is 20mg*16 tablets, and the price of a box is about 4,000.

Please note that this instruction manual is for reference only, and the specific usage and dosage should follow the guidance of your doctor. If you have any questions or discomfort, please seek medical advice in time.