What are the common side effects of nintedanib?

Nintedanib (Nintedanib) is a commonly used drug used to treat certain types of lung disease, such as idiopathic pulmonary fibrosis and non-small cell lung cancer. While nintedanib has shown significant efficacy in treating these conditions, there are some common side effects that patients and doctors should be aware of.

First, one of the most common side effects is diarrhea. Nintedanib affects the function of the digestive tract, causing large amounts of water to be excreted from the intestines, causing diarrhea. Some patients may need to go to the toilet more frequently and experience symptoms of diarrhea, which may cause some inconvenience to their daily lives. Nausea and vomiting are also common side effects of nintedanib. Because nintedanib has a certain irritating effect on the stomach, some patients may feel nauseated and may vomit during the medication. These side effects are usually most noticeable when you first start using the medication, but they usually lessen or disappear over time.

Additionally, nintedanib may cause abdominal pain, decreased appetite, and weight loss. Abdominal pain may be caused by the effects of medications on the intestines, causing abdominal discomfort. Decreased appetite and weight loss may be due to the medication affecting the patient's appetite and ability to absorb nutrients.

In addition to the common side effects mentioned above, nintedanib has some rarer but more serious side effects. For example, nintedanib may cause drug-induced liver injury, manifested by symptoms such as abnormal liver function tests and jaundice. At the same time, patients taking nintedanib may also experience bleeding, especially in the gastrointestinal tract.

In addition, there are reports that side effects such as proteinuria, pancreatitis, rash, and itching may occur during the use of nintedanib. Although these side effects are rare, they still require sufficient attention from patients and doctors.