What are the specifications and price of nintedanib?

Nintedanib is approved for sale in the form of oral capsules containing the kinase inhibitornintedanib. Nintedanibcomes as esylate. Oral nintedanib capsules are available in two dosage strengths, containing 100 mg or 150 mg of nintedanib (equivalent to 120.40 mg or 180.60 mg of nintedanib ethanesulfonate, respectively).

Nintedanib is indicated for the treatment of idiopathic pulmonary fibrosis (IPF) and slows down the decline in lung function in patients with systemic sclerosis-related interstitial lung disease; it is also indicated for the treatment of chronic fibrotic interstitial lung disease with a progressive phenotype. Nintedanib's benefits outweigh its risks and is effective in slowing lung function deterioration in patients with IPF, systemic sclerosis-related interstitial lung disease, and other progressive chronic fibrosing interstitial lung diseases. Regarding safety, relevant side effects are thought to be manageable by interrupting or reducing dosage.

The original drug of nintedanib, in the form of nintedanib ethanesulfonate soft capsules (trade name: Vigat/OFev), has been launched in the domestic market. At the same time, thanks to the relevant policies of the national medical insurance, the drug has been included in the Class B medical insurance reimbursement list. However, this discount is only available to qualified patients, and those who do not meet the requirements must bear the cost of the medicine. The common packaging specifications of medicines are 100mg 30 pills/box and 150mg 30 pills/box, with market prices starting at about 4,000 yuan.

Overseas, the original drug of nintedanib also has versions in Turkey and India. They are sold in specifications of 100 mg 60 pills and 150 mg 60 pills per box. The price is approximately between 4,000 and 5,000 yuan, depending on exchange rate changes. In addition, overseas markets also provide generic drug options. These drugs are similar in ingredients to original drugs and are produced by Indian BDR Pharmaceuticals, Laos ASEAN, Bangladesh Beacon and other pharmaceutical factories. The price is relatively low, about more than 600 yuan per box, but they are also affected by the exchange rate.