How much does a box of troagliptin cost in 2024?

Trelagliptin (Trelagliptin) is a drug used to treat type 2 diabetes. It belongs to the class of drugs called dipeptidyl peptidase-4 inhibitors (DPP-4 inhibitors). Diabetes is a chronic metabolic disease characterized by persistently elevated blood sugar levels. Type 2 diabetes is the most common type and is mainly caused by insulin resistance and insufficient insulin secretion. Tretagliptin helps control blood sugar levels by regulating the metabolic processes of insulin and blood sugar.

Trelagliptin, as aDPP-4 inhibitor, its mechanism of action is to improve pancreatic islet function by inhibiting the activity ofDPP-4 enzyme, thereby reducing blood sugar levels. DPP-4 enzyme is an enzyme that degrades glucagon (GLP-1) and pancreatic islet polypeptide-1 (GIP), two hormones that play an important role in the regulation of blood sugar. The inhibitory effect of trolagliptin can increase the concentration of GLP-1 and GIP in the body, thereby increasing the secretion of insulin and inhibiting the decomposition of glucagon, thereby reducing blood sugar levels.

The original drug of trotagliptin has not been approved for marketing in China, so it cannot be covered by medical insurance, and its price cannot be known yet. The original trotagliptin drug currently on the market overseas may cost more than RMB 1,000 per box of 50 mg*20 tablets, and may cost more than RMB 2,000 per box of 100 mg*20 tablets (the price may fluctuate due to exchange rates). There are also generic trotagliptin drugs produced in other countries overseas, and their drug ingredients are basically the same as those of the original drug. For example, the price of a box of 100mg*21 tablets produced by a Bangladesh pharmaceutical factory may be more than RMB 600 (the price may fluctuate due to exchange rates).