How much does a box of domestically produced cabozantinib cost?

Cabozantinib (Cabozantinib) is a drug used to treat specific types of cancer. However, there are currently no original cabozantinib drugs or generic drugs on the market in China. Therefore, there is no domestic generic drug cabozantinib developed, marketed and sold, and the price of domestic cabozantinib cannot be determined. Cabozantinib is mainly sold in overseas markets in two forms: tablets and capsules. For many patients, they may choose to purchase an overseas version of cabozantinib or find other more affordable treatment options.

Cabozantinib tablets are a cancer drug containing the active substancecabozantinib. It is used to treat adults with medullary thyroid cancer, a cancer that originates in the cells of the thyroid gland that produce the hormone calcitonin. Cabozantinib is used when the cancer cannot be removed with surgery and has progressed or spread to other parts of the body. The benefit of cabozantinib may be smaller in patients with cancer who do not have a mutation in a gene called "rearrangement during transfection" (RET) in the cancer gene, which should be considered when deciding whether to start treatment. Because the number of patients with medullary thyroid cancer is small and the disease is considered a "rare disease," cabozantinib was designated an "orphan drug" (a drug used for rare diseases).

Cabozantinib capsules are also a cancer drug that is used in patients with advanced renal cell carcinoma (kidney cancer) who have previously been treated with a cancer drug called a "vascular endothelial growth factor (VEGF) inhibitor"; it is mainly used in patients who have not received previous treatment and whose cancer is at moderate or high risk of getting worse. Cabozantinib capsules are also used alone for patients with hepatocellular carcinoma (a type of liver cancer) who have been treated with the cancer drug sorafenib; for differentiated thyroid cancer (a type of cancer that originates in the follicular cells of the thyroid) when the cancer has progressed or spread locally or to other parts of the body after systemic treatment (affects the entire body); when the cancer does not respond to radioactive iodine therapy, or in patients who cannot use radioactive iodine.

There are Japanese, Turkish and European versions of cabozantinib overseas, including60mg*30 tablets and (20mg+80mg)*112 capsules, with prices of more than 30,000 and 40,000 yuan respectively (exchange rate changes may cause price fluctuations). At the same time, there are also generic cabozantinib drugs in overseas markets, such as those produced in Bangladesh. The price is more affordable, only more than 2,000 yuan, and the efficacy is equivalent to the original drug.

In summary, there are currently no genuine cabozantinib drugs or generic drugs on the market in China, so the price of domestic cabozantinib cannot be determined. For patients who need to use this drug, they need to choose the appropriate purchase channel and treatment plan under the guidance of a doctor to ensure the safety and effectiveness of the drug.