Where can I buy Platinib in China and how much does it cost?

Pralsetinib, trade nameGavreto, is a drug approved for the treatment of RET mutation-positive medullary thyroid cancer (MTC), non-small cell lung cancer (NSCLC), and RET fusion-positive differentiated thyroid cancer (DTC) refractory to radioactive iodine (RAI) therapy. Platinib is a tyrosine kinase inhibitor that is used only if the patient's cancer has a specific genetic marker (an abnormal "RET" gene fusion), and your doctor will test the patient for the gene fusion.

Platinib is administered orally, and the most common adverse reactions include increased aspartate aminotransferase (AST), decreased hemoglobin, lymphopenia, neutropenia, increased alanine aminotransferase (ALT), increased creatinine, increased alkaline phosphatase, fatigue, constipation, musculoskeletal pain, decreased calcium, hypertension, decreased sodium, decreased phosphate, and thrombocytopenia.

The original drug Platinib has been launched in the domestic market, but unfortunately it is not covered by medical insurance. Its common packaging is 100mg 60 capsules and 100mg 120 capsules. The price is expensive, about more than 20,000 yuan per box, and even soaring to 60,000 yuan in some areas. The drug may be sold in domestic hospitals or pharmacies, and patients need to rely on the doctor's prescription information to purchase the drug.

In comparison, the price of foreign original drug Platinib is even higher.The price of each box of 60 pills fluctuates between 40,000 to more than 100,000 yuan (exchange rate changes may cause price fluctuations). The good news is that the first generic version of Platinib has been released overseas. Its ingredients are roughly the same as the original drug sold at home and abroad. The price of a box of 120 pills produced in Laos is about more than 4,000 yuan (the price may fluctuate with the exchange rate).