How many tablets of Eltrombopag/Eltrombopag should be taken at a time?
Eltrombopag/Eltrombopag is available as tablets and powder, and can be made into a suspension (liquid) for oral administration. Tablets contain the equivalent of 12.5 mg, 25 mg, 50 mg or 75 mg, and oral suspensions are available in 12.5 mg or 25 mg. This medication is available by prescription only, and treatment should be initiated and supervised by a physician experienced in treating blood disorders or chronic hepatitis C and its complications. Dosage is based on the patient's age and the condition eltrombopag is used to treat; adjust as needed to maintain appropriate platelet levels.
1. Spontaneous (immune) thrombocytopenia:
(1) Adult patients: In patients with inadequate response to corticosteroids and immunoglobulins or splenectomy, the initial dose is 50 mg once daily, with dosage adjusted for maintenance. Maintain platelet count ≥50x10^9 cells/liter. The maximum dose is 75mg/day.
(2) Pediatric patients:Children aged 1-5 years old, the initial dose is 25mg/time/day. For children 6-17 years of age, the dosage is the same as for adults.
2. Aplastic anemia: In adults with severe disease, unresponsive to immunosuppressive therapy, and unfit for hematopoietic stem cell transplantation, the initial dose is 50 mg once daily, titrated in 50 mg increments. Every 2 weeks to achieve and maintain platelet count ≥50x10^9 cells/L. The maximum dose is 150mg/day.
3. Thrombocytopenia associated with chronic hepatitis C: The initial dose for adults is 25 mg once daily, increasing by 25 mg every 2 weeks until a sufficient response is achieved to initiate antiviral treatment. The maximum dose is 100mg/day.
In general, the dosage of eltrombopag should be adjusted according to the patient's specific condition to ensure the effectiveness and safety of the drug. When using eltrombopag, patients should follow their doctor's recommendations and undergo regular examinations and monitoring.
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