How much does Crizotinib/Xalkori 250mg*60 tablets cost?

Crizotinib/Crizotinib contains the active ingredient Crizotinib, which is an oral anaplastic lymphoma kinase (ALK) inhibitor used to treat ALK or ROS1-positive non-small cell lung cancer, ALK-positive anaplastic large cell lymphoma and ALK-positive inflammatory myofibroblastic tumor. Crizotinib is indicated for the treatment of the following diseases:

-Adult patients with metastatic non-small cell lung cancer (NSCLC) whose tumors are positive for anaplastic lymphoma kinase (ALK) or ROS1 as tested by an FDA-approved test.

-Pediatric patients 1 year of age and older and adolescent patients with ALK-positive relapsed or refractory systemic anaplastic large cell lymphoma (ALCL).

-Adult and pediatric patients 1 year of age and older with ALK-positive unresectable, recurrent, or refractory inflammatory myofibroblastic tumor (IMT).

In the domestic market, the original drug crizotinib is sold in the form of crizotinib capsules (trade name: XALKORI/XALKORI) and is covered by medical insurance. This medicine is available in two specifications: 250 mg 60 pills and 200 mg 60 pills. Each box may cost more than 10,000 yuan. However, patients who meet the indication conditions can be reimbursed through national medical insurance. Similarly, in overseas markets, the price of the original drug crizotinib is also quite high, and each box may sell for more than 10,000 yuan, and the price may fluctuate with changes in exchange rates.

There are already lower-priced generics of crizotinib available overseas, and the ingredients of these generics are basically the same as the original drug. For example, the price of generic drugs produced in Bangladesh and Laos is only about 2,000 yuan in 250mg*60 capsules. However, the price will also change due to exchange rate fluctuations.