The best way to take cabozantinib and dosage

Cabozantinib is a multi-target tyrosine kinase inhibitor that has therapeutic effects on a variety of cancers. To ensure the effectiveness and safety of medications, correct administration and dosage are crucial.

The time taken for cabozantinib should be fixed to ensure a stable concentration of the drug in the body. It is usually recommended to take it at the same time every day to maintain stable blood levels. To avoid the effect of food on drug absorption, cabozantinib should be taken at least 2 hours before a meal or at least 1 hour after a meal. Make sure the medicine is fully dissolved in the stomach and absorbed in the small intestine. When taking cabozantinib, swallow the capsule whole and do not open, chew, or dissolve it. This helps ensure that the drug is released slowly in the intestines and maintains stable blood levels. If you miss a dose, take it as soon as you remember. However, if it is less than 12 hours before the next dose, skip the missed dose and take the next dose directly. Do not take double the dose at one time to make up for a missed dose. While taking cabozantinib, avoid foods (such as grapefruit) or nutritional supplements that may inhibit cytochrome P450 enzymes because they may affect the metabolism of the drug.

The dosage of cabozantinib varies for different cancers. For patients with thyroid cancer, the recommended dose of cabozantinib is 140 mg per day. This dosage usually requires a combination of one 80 mg pill and three 20 mg pills. Patients should continue taking the drug until disease progression or intolerable adverse reactions occur.

For lung cancer, liver cancer, kidney cancer and other conditions, the recommended dose of cabozantinib is 60mg per day. Likewise, patients should continue taking medications until their condition changes or the side effects of the medication become intolerable.