Is Apeliside produced in India a generic drug? How much?

Alpelisib (Alpelisib) is an oral PI3K inhibitor, mainly used to treat advanced or metastatic breast cancer carrying PIK3CA gene mutations. It inhibits the growth and spread of tumor cells by inhibiting the PI3K signaling pathway. In May 2019, Apelvis was approved for marketing by the U.S. Food and Drug Administration (FDA) and is recommended in combination with Fulvestrant for the treatment of advanced or metastatic breast cancer that is estrogen receptor (HR) positive, human epidermal growth factor receptor 2 (HER-2) negative, has PIK3CA gene mutations, and occurs in postmenopausal women and men. It has become the world's first targeted therapy for breast cancer PIK3CA mutations.

Regarding Apelvis produced in India, there is an original version, but there are also generic drugs produced by relevant pharmaceutical factories in Laos. The ingredients of these generic drugs are basically the same as the original drugs, but the price is much cheaper. Since the original drug of Apelvis is relatively expensive, many patients may choose to purchase generic drugs due to economic factors. However, it is important to note that the quality and safety of generic drugs may vary depending on the manufacturer and regulatory situation, so evaluation and consultation with a physician is required before use.

Apelvis is not yet on the market in China, so patients may need to consider purchasing it abroad if they need to use this drug. Specifications150mg*28 tablets per box of the original Indian version may be priced at more than 5,000 RMB (the price may fluctuate due to exchange rate effects); and the generic version of Lucius from Laos, specifications150mg*28 tablets may be priced at more than 2,000 RMB per box (price may fluctuate due to exchange rate effects). For more information on overseas drug prices and related information, please consult Yaode Medical Consultants.