Lao version of avatrombopag (Avatrombopag) detailed medication guide

Avatrombopag, as an effective drug for the treatment of thrombocytopenia, has been widely used clinically. However, due to the high price of original drugs, many patients turn to generic drugs. The launch of the Laotian version of avatrombopag has brought patients a cost-effective alternative. To ensure that patients can use this medication correctly and safely, a detailed medication guide is provided below.

1. Indications

The Lao version of avatrombopag is primarily used to treat thrombocytopenia associated with chronic liver disease, especially in patients who are scheduled to undergo surgery. It can also be used in patients with chronic immune thrombocytopenia who do not respond well to standard treatments.

2. Medication dosage and usage

1. Chronic liver disease:

Platelet count less than40 x 10⁹/L: 60 mg orally daily starting 10 to 13 days before scheduled surgery.

Platelet count40 to less than 50 x 10⁹/L: 40 mg orally once daily starting 10 to 13 days before scheduled surgery.

Treatment duration:5 days

Comments: Patients should receive treatment 5 to 8 days after the last dose.

2. Chronic immune thrombocytopenia:

Once a day, each time20 mg. Adjust dose or dosing frequency to maintain platelet count greater than or equal to 50 x10⁹/L. Do not exceed 40 mg per day.

3. Precautions

1. Before starting to use the Lao version of avatrombopag, patients should report to their doctor in detail their allergy history, disease history, and all medications they are currently taking to avoid potential drug interactions.

2. Pregnant and lactating women should specifically consult their doctor before use, as it is currently unclear whether this drug will affect the fetus or infant.

3. Patients should undergo regular platelet count checks during the medication period to ensure that the platelet count is within a safe range.

4. If you experience any discomfort or abnormal reactions, such as high fever, persistent bleeding, severe headache, etc., you should seek medical attention immediately.

4. Possible side effects and treatments

The Lao version of avatrombopag may cause some side effects, common ones include fever, easy bruising or bleeding (such as nosebleeds, bleeding gums), purple or red spots on the skin, fatigue, headache, joint pain, cold symptoms (runny nose, stuffy nose, sneezing, sore throat), nausea, stomach pain, and swelling of the hands or feet. Most side effects are mild and reversible, but if symptoms persist or worsen, seek medical attention promptly.

5. Storage and disposal

Lao version of Avatrombopag should be stored in a dry, cool place away from direct sunlight. At the same time, the medicine should be kept out of the reach of children to prevent accidental ingestion.

6. Specifications and selling price

There are multiple manufacturers selling generic versions of avatrombopag in the Lao market. It is understood that the Lucius version is priced at around 800 per box (20mg*28 tablets), the ASEAN version (20mg*15 tablets) is priced at around 300 per box, and the United Pharma version (20mg*30 tablets) is priced at around 800 per box.

All in all, the launch of the Lao version of avatrombopag provides patients with some affordable options, but doctors’ instructions and medication guidelines must be strictly followed when using it to ensure patient safety and efficacy.