Where can I buy Apelvis tablets in China?

Alpelisib (Alpelisib) is an innovative drug specifically targeting breast cancer, especially advanced or metastatic breast cancer that is hormone receptor (HR) positive, human epidermal growth factor receptor 2 (HER2) negative, and has PIK3CA gene mutations. Apelix, as a PI3K inhibitor, slows or prevents the proliferation of cancer cells by inhibiting the PI3K protein, which is critical for cancer growth. This drug was approved by the FDA in the United States in 2019 and can be used in combination with fulvestrant to extend the progression-free survival of patients. Apelix selectively inhibits PI3Kα, thus directly targeting the effects of activating mutations in PIK3CA. In a study of PIK3CA or TEK mutations, Apelvis reversed abnormal AKT phosphorylation, cell morphology, and extracellular fibronectin levels—further emphasizing the link between TIE2 and PI3Kα in the cause of common venous malformations.

The original drug of Apelvis is not yet available for sale in China, and patients in need can only obtain it through relevant overseas channels. According to the regulations of the National Medical Products Administration, Apelvis tablets are prescription drugs and require a doctor's prescription to purchase. If the drug can be marketed in the country, domestic hospitals and pharmacies may supply it. With the development of the Internet, more and more patients tend to purchase drugs through online pharmacies. No matter which purchasing channel you choose, you should ensure the reliability of the source of the medicine and avoid purchasing fake and shoddy products. When purchasing, carefully check the packaging, labels, instructions and other information of the medicine to ensure that you are purchasing genuine products. When using Apelvis, you should follow your doctor's advice and instructions and use it in accordance with the prescribed dosage and usage.