How much does a box of Platinib cost?

Pratinib is a drug used to treat metastatic RET-driven non-small cell lung cancer. It exerts anti-tumor effects by specifically inhibiting the RET receptor tyrosine kinase rearranged during transfection. This drug can selectively inhibit the activity of RET kinase, thereby interfering with the proliferation, survival and differentiation of tumor cells and controlling tumor progression.

Platinib can also inhibit the activation of angiogenic signaling pathways such as vascular endothelial growth factor receptor (VEGFR), reducing tumor blood vessel formation and blood supply. In this way, it can slow down tumor growth and help shrink or stabilize tumors.

This drug has not been included in the scope of medical insurance reimbursement. In the domestic market, its latest price is about more than 20,000 yuan to 60,000 yuan. At the same time, there are two original developed versions on the overseas market, namely the American version and the European version. It is understood that the latest price of the American version of platinib is about 16 yuan, while the European version is about 4.5 yuan. In addition, the Ministry of Health of Laos has approved the listing of a generic drug Platinib. Its pharmaceutical ingredients are basically the same as the original drug. The latest price is about four to five thousand yuan.

Platinib is mainly used to treat a certain type of non-small cell lung cancer (NSCLC) that has spread to other parts of the body. In addition, it is indicated to treat certain types of thyroid cancer in adults and children 12 years and older that are getting worse or have spread to other parts of the body.

Gastrointestinal problems such as nausea, vomiting, and diarrhea may occur while using platinib. In addition, it may have adverse effects on liver function, so liver function indicators need to be checked regularly. Platinib is contraindicated in pregnant women, lactating women and patients with severe hepatic impairment.