How much does a box of Mitotan cost in China?

Mitotane (Mitotane), also known as Lysodren, is a drug used to treat adrenocortical cancer (ACC) and Cushing's syndrome. It is a selective poison of the adrenocortical cells, destroying these cells and thus reducing the production of excess hormones. Mitotane plays an important role in treating these conditions, especially when surgery cannot completely remove the tumor or the cancer has spread.

Mitotane is currently on the market in China, but it has not yet been included in medical insurance. Since it is difficult to purchase soon after it is launched, please consult the local hospital pharmacy for details. There are original drugs and generic drugs abroad. The original drugs are mainly European versions of original drugs. The price is more than 9,000 yuan, which is relatively high. The cheaper ones abroad are generic drugs, mainly Lao generic drugs, which cost about one to two thousand yuan, and the ingredients of the drugs are basically the same as the original drugs.

Mitotane acts by affecting the function and structure of adrenocortical cells. It inhibits the synthesis of adrenocortical hormones, especially cortisol and other glucocorticoids. In addition, Mitotane also selectively destroys adrenocortical cells, thereby reducing the problem of tumor tissue and excessive hormone secretion.

Mitotane is used to treat adrenocortical carcinoma (ACC), a rare but aggressive cancer. It is also used to treat adrenal hyperplasia or cancer that cannot be completely removed by surgery, and to treat Cushing's syndrome, a condition caused by too much cortisol in the body. For patients with adrenocortical cancer, Mitotane can be used as adjuvant therapy to help prolong survival and improve symptoms.

Although Mitotane has significant therapeutic effects, its side effects are also significant. Common side effects include gastrointestinal effects, such as nausea, vomiting, diarrhea, and loss of appetite; neurological symptoms, such as dizziness, ataxia, and confusion. In addition, Mitotane may cause abnormal liver function and leukopenia. Due to its possible serious impact on adrenocortical function, patients need to regularly monitor blood and liver function indicators during the use of mitotane, and may need to supplement hormone replacement therapy to maintain hormone balance in the body.