How much does a box of acotinib/acabrutinib capsules cost?

Acalabrutinib/Acalabrutinib is used to treat patients with mantle cell lymphoma (MCL; a fast-growing cancer that starts in immune system cells) who have been treated with at least one other chemotherapy drug; it is also used alone or with obinutuzumab to treat chronic lymphocytic leukemia (CLL; a cancer that starts in white blood cells) and small lymphocytic lymphoma (SLL: a cancer that starts in white blood cells). Acotinib belongs to a class of drugs called kinase inhibitors. It works by blocking the action of abnormal proteins that signal cancer cells to multiply. This helps stop the spread of cancer cells.

Acotinib is a member of the BTK inhibitor classoften used in chronic lymphocytic leukemia and mantle cell lymphoma. Acotinib is an oral medication that is usually taken every 12 hours with or without food (twice a day) for as long as your doctor advises you to take this medication. Take acotinib at about the same time each day, and do not take more or less of your dose than prescribed by your doctor. Swallow medicines whole with a glass of water; do not open, chew, or break them.

The original drug of acotinib capsules has been launched in China and is included in the reimbursement scope of Class B medical insurance. Reimbursement is limited to patients who meet the indications. The specification is 100mg*8 capsules*7 tablets, and the price may be more than 40,000 yuan per box; while the original drug sold overseas, the price of 100mg*60 tablets per box may be more than 10,000 U.S. dollars, which is very expensive. However, there are already generic acotinib drugs produced and sold overseas, and their drug ingredients are basically the same as the original drugs at home and abroad. For example, the price of a box of 100mg*60 tablets produced by Laos Pharmaceuticals may be more than 3,000 yuan (the price may fluctuate due to exchange rates).