Semaglutide tablets efficacy, functions and price

Semaglutide tablets (Rybelsus) is an oral medication used to improve blood sugar control in adults 18 years of age and older with type 2 diabetes. It can be used as a first-line treatment in addition to diet and exercise or other medications typically used for type 2 diabetes.

Semaglutide tablets belong to a class of drugs calledGLP-1 receptor agonists. It may also be called an incretin mimetic.

Semaglutide tablets work by mimicking the function of natural incretin in the body, helping to control blood sugar levels, especially after meals. Incretins are intestinal peptides secreted from the stomach when you eat. They also stimulate the secretion of insulin in response to high blood sugar levels. The two incretin hormones are called GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1).

In people with type 2 diabetesthe natural release of incretin is reduced or no longer present. However, it can be stimulated by pharmacological agents, such as asparagus.

Semaglutide tablets share 94% of the same structure as human GLP-1GLP-1, but it is man-made. It acts similarly to GLP-1 and binds to the GLP-1 receptor, stimulating the pancreas to release insulin, reducing glucagon secretion by the liver, and making people feel full by slowing gastric emptying.

Semaglutide tablets only need to be taken once a day rather than after each meal because it binds to albumin, which slows down its excretion through the kidneys and protects it from being metabolized (broken down) by an enzyme naturally found in the blood called dipeptidyl peptidase-4, or DPP-4.

Although semaglutide tablets were only approved for marketing in China this year, because it is a new product on the market, domestic patients may not be able to purchase it immediately. At this time, we can refer to the semaglutide tablets that are already on the market overseas, for example, the overseas original research versionThe price of 3mg*100 tablets is around 2,000 yuan. At the same time, there are a variety of other specifications of oral semaglutide available in overseas markets. If you want to know more details, it is recommended to consult a professional overseas medical consultant.