Is cycloserine included in domestic medical insurance? How much?

Cycloserine (Cycloserine) is an antibiotic used to treat tuberculosis and other bacterial infections. In 1952 it was first isolated from actinomycetes and quickly demonstrated its importance in anti-tuberculosis treatment.

Cycloserine is an amino acid derivative that belongs to the β- lactam antibiotics. Its mechanism of action is to competitively inhibit D-alanine-D-alanine ligase, thereby preventing the cross-linking of peptidoglycan, interfering with the synthesis of bacterial cell walls, leading to bacterial death. Cycloserine exhibits significant activity against multiple drug-resistant strains and is therefore particularly important in the treatment of multidrug-resistant tuberculosis (MDR-TB).

Clinically, cycloserine is usually used as a second-line drug to treat drug-resistant tuberculosis, especially in patients who are resistant to first-line drugs such as isoniazid and rifampicin. Cycloserine is well absorbed orally and can effectively penetrate into various tissues and body fluids of the human body, including the lungs and cerebrospinal fluid, thus having a good therapeutic effect on infections such as tuberculosis and tuberculous meningitis.

However, the use of cycloserine is also associated with some adverse effects. Common central nervous system side effects include headache, dizziness, insomnia, depression and anxiety, and in severe cases may cause epilepsy and psychotic symptoms. Therefore, during treatment with cycloserine, patients need to be closely monitored by a doctor so that the dose can be adjusted or discontinued in a timely manner.

In terms of price and medical insurance, cycloserine is now available in China and has been included in medical insurance. This means that patients can reimburse part of the cost through medical insurance, reducing their burden. In terms of specific price, the price of domestically produced cycloserine with a specification of 250mg*10 capsules is about a few hundred yuan. Since policies vary from place to place, patients need to consult the local hospital pharmacy for specific reimbursement ratios and out-of-pocket portions.

In addition, Indian generic drugs abroad are relatively cheap. The specification is 250mg*60pills and the price is about 600 yuan. Indian generic drugs have basically the same ingredients as domestic drugs, providing a more economical option.