Apremilast/Apremilast Tablets Medication Guide: Important Precautions and Recommendations

Apremilast Apremilast is an oral medication indicated for the treatment of moderate to severe plaque psoriasis in adults who are indicated for phototherapy or systemic therapy.

Before taking medication, patients should describe their special allergy history, physical condition, underlying diseases, and recent medication use to the doctor in detail, so that the doctor can evaluate whether there are any contraindications to medication and avoid serious medication risks. This product may increase the risk of pregnancy termination, so women of childbearing potential should practice pregnancy planning and prevention. While taking this medication, if a female patient plans to become pregnant or is suspected of becoming pregnant, she should inform her doctor immediately.

Patients receiving Apremilast/Apremilast tablets should monitor their weight regularly. If unexplained or clinically significant weight loss occurs, weight loss should be evaluated and discontinuation of the drug should be considered. Concomitant use of potent cytochrome P450 enzyme inducers (e.g., rifampicin, phenobarbital, carbamazepine, phenytoin) may result in decreased systemic exposure of this product and may result in loss of efficacy. Therefore, combined use with these drugs is not recommended. If patients need to use other drugs while taking this medication, they should consult their doctor or pharmacist.

This product can be taken without regard to meals, but do not crush, break or chew the tablets. Swallow the tablets whole. At the same time, please keep this product out of reach of children to prevent children from accidentally taking it.

Patients should pay close attention to physical reactions during medication. If adverse reactions such as diarrhea, nausea, vomiting, depression, etc. occur, they should seek medical treatment promptly and inform the doctor. Doctors should carefully weigh the risks and benefits before using this product, especially in patients with a history of depression and suicidal thoughts or behaviors. Patients should follow the doctor's recommendations for regular follow-up visits so that the doctor can evaluate the treatment effect and adjust the medication plan.

In addition to drug treatment, patients should also maintain a healthy lifestyle, such as a balanced diet, moderate exercise, and adequate sleep, to promote recovery from the disease.