How many boxes of sotoraxibu (AMG510) should be consumed in a month?

Sotorasib (AMG510, Sotorasib) is an experimental KRAS inhibitor under investigation for the treatment of KRAS G12C mutant non-small cell lung cancer (NSCLC). Sotoraxib, taken orally once daily, is the first approved drug to inhibit KRASG12C; it permanently binds to KRASG12C and locks it in an inactive state. In clinical trials, a clinically relevant proportion of patients responded to treatment with sotoraxib, and the duration of response was considered clinically relevant. Adverse effects of treatment are manageable; dose reduction and/or treatment with sotoraxib can be temporarily discontinued to control adverse effects.

From the perspective of drug specifications, sotoraxib has different tablet specifications, such as120mg and 320mg. The standard dose of sotoraxib is usually 960 mg once daily, which means patients need to take a sufficient number of tablets per day to achieve this dose. Therefore, if a patient is using 120mg tablets, then they need to take 8 tablets per day, 240 tablets for a month (based on 30 days), that is, one box (each box contains 120mg*240 tablets) or more, depending on the number of tablets per box.

Patients may encounter various situations during the actual medication process, such as missed doses, dose adjustments, etc., which may affect the amount of medication taken within a month. In addition, the patient's condition and the doctor's prescription are also important factors in determining the dosage of medication. Therefore, patients should strictly follow the doctor's instructions when taking medication and maintain communication with the doctor during the medication process to ensure the safety and effectiveness of the medication.

In addition, regarding the sales of sotorasibu in the Chinese market, although the drug has not yet been officially launched in mainland China, patients can purchase the drug through some special channels, such as participating in clinical trials.