How many pills of sotoraxibu (AMG510) should be taken a day?

As a targeted drug targetingKRAS G12C mutation, the dosage of Sotorasib (AMG510, Sotorasib) is determined based on clinical studies and drug characteristics. According to its package insert, the recommended dose of sotoraxib is 960 mg orally once daily. Because sotoracib is usually available in tablet form, and each tablet has a dose of 120 mg, to achieve the recommended daily dose of 960 mg, a patient would need to take 8 tablets of sotoracib. Patients should pay attention to the following points when taking sotoraxib:

1. Take the medicine on time: Take sotorasiib at approximately the same time every day to ensure a stable concentration of the medicine in the body and achieve optimal efficacy.

2. Swallow the tablet as a whole: Sutoraxibu should be swallowed as a whole. Do not chew, crush or break the tablet to avoid affecting the release and absorption of the drug.

3. Take it with food: Sotolaxib can be taken with or without food, which can be decided according to the patient's personal habits and comfort level.

4. Pay attention to adverse reactions: During the period of taking sotorasib, patients may experience some adverse reactions, such as diarrhea, musculoskeletal pain, nausea, fatigue, etc. If serious or persistent adverse reactions occur, you should report it to your doctor promptly.

5. Follow the doctor’s instructions: The most important thing is that patients should strictly follow the doctor’s instructions and recommendations to take sotorasiib, and do not change the dosage or stop taking it without authorization.

In addition, it is worth noting that sotorasibu is not currently available in China, but it has been approved in the United States and other countries and regions for the treatment of patients with locally advanced or metastatic non-small cell lung cancer with KRAS G12C mutations. Therefore, for domestic patients, if they need to use sotoraxib for treatment, they may need to obtain the drug through specific channels or ways and follow the guidance and recommendations of their doctors.