Ruxolitinib Ointment Detailed Instructions for Patients

Drug name: Ruxolitinib ointment (Opzelura)

Ingredients: Each gram of ruxolitinib ointment contains 15mg of ruxolitinib, its main ingredient is JAK1/JAK2 inhibitor.

Indications: Ruxolitinib ointment is used to treat vitiligo and mild to moderate atopic dermatitis (eczema). Its mechanism of action is to reduce the inflammatory response and relieve related symptoms by inhibiting the activity of JAK1 and JAK2 kinases.

How to use:

1.Clean skin: Before using ruxolitinib ointment, make sure the affected skin area is clean and dry. Clean skin with mild soap and water, then pat dry.

2.Dosage: Take an appropriate amount of ruxolitinib ointment (usually a strip of ointment 1-2cm long) and apply it evenly on the affected skin area. After application, massage gently until completely absorbed. Avoid overdosing.

3.Frequency of use: Twice a day, once in the morning and once in the evening. Depending on the severity of your symptoms, your doctor may adjust the frequency of use. Follow your doctor's specific instructions for best results.

4.Treatment cycle: The treatment cycle varies depending on individual differences and the severity of the disease. Typically, treatment takes weeks to months. The doctor will conduct regular evaluations based on the progression of the disease and decide whether the treatment needs to be adjusted or discontinued.

5.Notes:

Avoid contact with eyes and mucous membranes: Avoid contact with eyes, mouth and other mucosal areas with ruxolitinib ointment. In case of accidental contact, rinse immediately with plenty of water.

Not for use on broken skin: Avoid using this medication on broken, inflamed, or infected skin to avoid worsening the skin problem.

Avoid use on large areas: Long-term use of ruxolitinib ointment on large areas of skin is not recommended to reduce the risk of systemic side effects. It should be used only on the affected area and as recommended by your doctor.

Avoid mixing with other topical drugs: If you need to use other topical drugs at the same time, it is best to consult a doctor to avoid drug interactions.

Use a moisturizer: During the use of ruxolitinib ointment, it is necessary to keep the skin moisturized. You can use a non-irritating moisturizer under the advice of your doctor.

6.Side effects:

Common side effects: May include local skin reactions such as dryness, irritation, redness, or itching. Usually these side effects are mild and will ease as you get used to them.

Serious side effects: A very small number of patients may experience allergic reactions such as severe redness, swelling, rash, or itching. If these symptoms occur, stop taking the medication and seek medical advice immediately.

Infection risk: Long-term use may increase the risk of local infection. Keeping your skin clean and avoiding scratching can help reduce the risk of infection.

7.Discontinuation and adjustment:

If symptoms improve significantly, your doctor may recommend reducing the frequency of use or discontinuing the medication. After discontinuation, other moisturizing measures or adjunctive treatments may need to be continued to maintain skin health.

If you experience any discomfort or worsening of symptoms during use, you should contact your doctor promptly and adjust the treatment plan if necessary.

Save:

Store ruxolitinib ointment at room temperature, away from light, and away from children. Avoid exposing this medicine to high temperatures or moisture.

Notes:

Before using the medicine, please read the instructions carefully and use it under the guidance of a doctor. Do not adjust the medication regimen or frequency arbitrarily.

Consult a doctor:

While using ruxolitinib ointment, follow up regularly to evaluate the treatment effect and adjust the drug usage plan. If you have any questions or adverse reactions, please consult your doctor promptly.

This instruction sheet is intended to provide patients with guidance on the use of ruxolitinib ointment to ensure safe and effective treatment. If you have any questions, please consult your doctor or pharmacist.