Where to buy Canafenib/Encofenib

Encorafenib, which has the active substance encorafenib, is a drug used in adults to treat certain cancers when their cells have a genetic mutation (change) called "BRAF V600." In cancers with BRAF V600 mutations, there is an abnormal form of the BRAF protein that turns on another protein called MEK, which is involved in stimulating cell division. This encourages the development of cancer by allowing uncontrolled cell division. Canafenibworks by blocking the BRAF protein, thereby stopping its activation of cell division and slowing the growth and spread of cancer.

Canafenib is often used in combination with another drug, binimetinib, to treat melanoma (a type of skin cancer that cannot be removed with surgery or has spread), non-small cell lung cancer (when the cancer is advanced and has a mutation in the V600E version of BRAF); Canafenib is also used in combination with the drug cetuximab to treat patients with BRAF The V600E mutated version of colorectal cancer (large intestine or rectum cancer) when it has spread to other places in the body and has been previously treated with other systemic (oral or injected) drugs.

The original drug of Canafenib has not yet been launched in China, so its price is not yet clear. For patients in need, this drug is not yet available in domestic hospitals or pharmacies, and may only be purchased through relevant overseas channels. Overseas, the European version of Canafenib's original drug is already on sale. The price of each box of 75 mg and 42 tablets may exceed RMB 10,000, and the price of each box of 75 mg and 168 tablets may be as high as more than RMB 40,000 (the price is affected by exchange rate fluctuations), which is very expensive. At the same time, no generic drugs of canafenib have been launched in domestic and foreign markets. For more information on overseas drug prices and related information, please consult Yaode Medical Consultants.