Can't I stop taking Platinib? What is the correct way to take it?

Platinib, brand name Pujihua, is a cancer treatment drug targetingRET gene mutation. As the first approved selective RET inhibitor in China, it is administered orally once daily, providing a new treatment option for patients with non-small cell lung cancer and medullary thyroid cancer. Platinib can effectively inhibit the phosphorylation of RET and its downstream molecules, thereby controlling the growth of cancer cells carrying RET gene mutations.

Recently, rumors about platinib that "once you start taking it, you cannot stop it" have attracted widespread attention. In fact, this statement is not accurate. The administration time and dosage of platinib should be individually adjusted based on the patient's specific condition and drug response. During the treatment process, doctors will regularly evaluate the patient's condition and drug effects to ensure the safety and effectiveness of the treatment.

It is worth noting that although platinib should not be discontinued at will, it is not set in stone. If a patient experiences serious adverse reactions during medication, or if the condition is effectively controlled and the expected effect is achieved, the doctor may consider adjusting the medication regimen or even discontinuing the medication. In addition, patients with serious underlying diseases should be more cautious when using platinib and strictly follow the doctor's instructions.

Regarding the specific dosage of platinib, the recommended dose for adults and children 12 years of age and above is 400 mg orally once daily. To ensure optimal absorption of the drug, Platinib should be taken on an empty stomach, that is, at least 2 hours before or 1 hour after a meal. If vomiting occurs shortly after taking the medication, the patient should not take the medication again but should wait until the next scheduled medication time.

During the period of medication, patients should maintain close communication with their doctors and promptly report any discomfort or abnormalities. At the same time, patients should also fully understand the principles and precautions for the use of Platinib to ensure the safe and effective use of the drug.

Finally, it should be emphasized that Platinib is a prescription drug and must be used under the guidance of a professional doctor. Patients should strictly follow the doctor's instructions during use and do not adjust the medication regimen or stop medication on their own to avoid unnecessary damage to the body.