What are the side effects of lapatinib?

Lapatinib (Lapatinib), trade name is Telisa, is an oral small molecule targeted anti-tumor drug, mainly used to treat advanced or metastatic breast cancer with overexpression of HER2 (human epidermal growth factor receptor 2). This drug inhibits tumor growth by specifically inhibiting the tyrosine kinase activity of HER2 and EGFR (epidermal growth factor receptor), thereby blocking the growth signaling of tumor cells.

While you are taking lapatinib, you need to pay close attention to how your body is reacting. Get emergency medical help immediately if you experience an allergic reaction, such as hives, difficulty breathing, swelling of the face or throat, or severe skin problems, such as fever, sore throat, burning eyes, sore skin, or a red or purple rash with blistering and flaking.

This medicine may cause serious or even fatal liver problems. If you develop upper abdominal pain, itching, dark urine, chalky stools, or jaundice (yellowing of the skin and eyes), contact your doctor immediately.

At the same time, the following symptoms also need to be taken seriously and the doctor should be notified immediately: rapid heartbeat, chest trembling, shortness of breath, sudden severe dizziness; persistent and severe diarrhea; and new or worsening cough, wheezing, chest pain, shortness of breath, etc.

In addition, common side effects of lapatinib include indigestion, loss of appetite, nausea, vomiting, diarrhea, rash, itching, dry skin, acne, pain or redness on the palms or soles of the feet, nail problems, weakness and fatigue, nose bleeding, mouth ulcers, thinning hair, and headaches. Please note that these are not all side effects and other side effects may occur. During use, if you have any discomfort, please communicate with your doctor in time.

Therefore, when using lapatinib to treat breast cancer, patients need to pay close attention to their body's reaction. If any discomfort occurs, they should communicate with their doctor and seek medical help in a timely manner. At the same time, doctors should also formulate a reasonable medication plan based on the patient's specific situation to minimize the occurrence of side effects and ensure patient safety and therapeutic effects.

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Reference materials:https://www.drugs.com/mtm/lapatinib.html