2025 Avatrombopag (Avatrombopag, Su Kexin) price for a box of 28 tablets

Avatrombopag/Avatrombopag is a new oral thrombopoietin receptor agonist, mainly used to treat specific diseases related to thrombocytopenia. Its main indications include patients with chronic immune thrombocytopenia (ITP) and chronic liver disease (CLD) combined with thrombocytopenia. In both cases, avatrombopag effectively increases platelet counts by stimulating megakaryocytes in the bone marrow and promoting platelet production.

Avatrombopag is widely used in the treatment of chronic immune thrombocytopenia (ITP). ITP is an autoimmune disease in which the patient's immune system mistakenly attacks and destroys platelets, resulting in a decrease in platelet count and a risk of bleeding. Avatrombopag activates the thrombopoietin receptor, enhances the proliferation and differentiation of megakaryocytes, and promotes the production of platelets, which is of great significance for improving patients' bleeding tendency and reducing the risk of bleeding events.

In addition, thrombocytopenia is a common complication in patients with chronic liver disease (CLD), often associated with hypersplenism and myelosuppression. It is critical for these patients to be able to maintain safe platelet levels while undergoing certain medical procedures or surgeries. The use of avatrombopag can effectively increase the platelet count in these patients, thereby reducing the risk of intraoperative and postoperative bleeding and providing patients with better treatment options.

In the domestic market, the original drug of avatrombopag has been launched and entered Class B medical insurance, but reimbursement is limited to eligible patients. Its common specifications are 20mg15 tablets or 20mg10 tablets per box, and the price may be as high as 7,000 yuan. Overseas, the price of this original drug is even more prohibitive. However, the good news is that generic drugs of avatrombopag have been launched overseas, and their ingredients are roughly the same as the original drug. For example, the 20mg*30 tablets produced by Laos Pharmaceuticals cost only more than 500 yuan per box, but the price may be affected by exchange rate fluctuations.

Reference materials:https://www.cda-amc.ca/avatrombopag