How should I take Mobotinib (Mobosetinib) correctly? What is the dose?

Mobotinib, as a prescription drug specifically targeting non-small cell lung cancer with EGFR exon 20 insertion mutations, must be used strictly under the supervision and guidance of a doctor. Before starting treatment, patients should fully understand the drug's mechanism of action, correct usage and dosage, and possible adverse reactions to ensure the safety and effectiveness of the entire treatment process.

When taking Mobotinib, patients should keep taking it at the same time every day, which will help maintain stable blood concentration and enhance the therapeutic effect. Capsules should be swallowed whole. Do not open, chew or dissolve the capsule contents to avoid damaging the drug structure and affecting absorption and efficacy.

If you accidentally miss a dose and it has been more than 6 hours, skip that dose and take the next dose at your regular time the next day. If vomiting occurs shortly after taking it, there is no need to take an additional dose. Just take the next dose as planned the next day. Importantly, patients should never stop taking medications on their own without the advice of their attending physician, as this may affect the effectiveness of the treatment.

Recommended dosage of mobotinib is 160 mg once daily and continued until disease progression or unacceptable toxicity. During treatment, if the patient experiences adverse reactions, the doctor may recommend adjusting the first dose to 120 mg once a day based on the patient's specific condition. If adverse reactions persist and the patient is still intolerant, the doctor may further adjust the dose to 80 mg once daily. It should be emphasized that any adjustments to the treatment plan must strictly follow the doctor's instructions, and patients are not allowed to change the dosage of the medication on their own.

In addition, while taking Mobotinib, patients should regularly monitor their physical condition, including important indicators such as cardiopulmonary function and blood routine, and communicate with their doctors in a timely manner. If you have any discomfort or questions, you should contact your doctor immediately and adjust the medication plan according to the doctor's advice to ensure the safety and effectiveness of the treatment.

References:

https://www.drugs.com/search.php?searchterm=Exkivity&sources%5B%5D=professional