How much does it cost to buy a box of Bosutinib/Bosutinib in 2025?

Bosutinib/Bosutinib is a cancer drug used to treat chronic myeloid leukemia (CML), which primarily affects adults with the Philadelphia chromosome. The drug is suitable for patients who have been treated with one or more tyrosine kinase inhibitors (TKIs), including cases in the "chronic phase", "accelerated phase" and "blast phase". Bosutinib can also be used as a treatment option when commonly used TKIs such as dasatinib, imatinib and nilotinib are not suitable. In addition, bosutinib is also indicated for patients with newly diagnosed chronic myelogenous leukemia.

The active ingredient of bosutinib isbosutinib, which is a tyrosine kinase inhibitor that mainly works by inhibiting the activity of two tyrosine kinases, Src and Bcr-Abl. These enzymes play an important role in leukemia cells by promoting uncontrolled cell proliferation. By blocking the function of these enzymes, bosutinib can effectively control the growth and spread of CML cells, helping patients better manage their disease.

Currently, the original drug of bosutinib has not yet been launched in China, so there is no clear information on its specific price. At this stage, there are Swiss, Turkish and European versions of the original drug on the overseas market. The Turkish version500 mg 28 tablets are priced at about 2,000 yuan, while the European and Swiss versions may be priced close to 40,000 yuan, and may change due to exchange rate fluctuations. In addition, there are generic bosutinib drugs from other countries, whose ingredients are similar to the original drug. For example, a box of 100 mg and 120 tablets produced in India may be sold for more than 1,000 yuan per box, which is relatively economical. For more information on overseas drug prices and related information, please consult Yaode Medical Consultants.

Reference materials:https://www.ema.europa.eu/en/medicines/human/EPAR/bosulif