Dietary precautions and nutritional suggestions during Tepotinib (Tuodekang) treatment

Tepotinib is an oral MET inhibitor mainly used to treat patients with non-small cell lung cancer with MET exon 14 skip mutations. During treatment, a reasonable diet not only helps maintain the patient's physical strength, but also reduces the occurrence of drug-related adverse reactions. Patients should eat a light, easily digestible, nutritionally balanced diet, avoid high-fat, high-sugar and salty foods, and ensure adequate water intake to support body metabolism and drug absorption.

While taking tepotinib, some patients may experience gastrointestinal reactions such as nausea, vomiting, diarrhea, or loss of appetite. In response to these situations, it is recommended to eat small amounts with frequent meals to avoid consuming large amounts of food at one time. You can choose foods that are high in protein, low in fat, and rich in complex carbohydrates, such as lean meats, fish, soy products, whole grains, and fruits and vegetables. At the same time, resting for half an hour to an hour after meals and reducing strenuous activities can help relieve nausea and stomach discomfort.

Tepotinib treatment may lead to weight loss or malnutrition, so attention should be paid to protein and trace element intake. You can consume high-protein foods such as eggs, fish, dairy products, and nuts in moderation to maintain muscle mass and immune function. At the same time, pay attention to supplementing vitamins and minerals, such as vitamin C, vitamin D, calcium and magnesium, etc., to help enhance the body's resistance. If the amount of oral food is insufficient, high-protein nutritional powder or oral supplements can be used under the guidance of a doctor.

Patients should try to avoid irritating foods, such as spicy, fried and overly sweet foods, to reduce gastrointestinal discomfort while taking the medication. In addition, caffeine and alcohol may affect drug metabolism or aggravate adverse reactions and should be limited as much as possible. It is best to keep a certain interval between taking the medicine and meals. You can choose to take it before or after meals according to the doctor's advice, but it must be maintained regularly. Overall, combining scientific diet and nutritional supplements can help improve patients' treatment compliance and quality of life, while optimizing the efficacy of tepotinib.

Reference link:https://www.drugs.com