What is the Difference Between Enzalutamide (Enzalutamide) and Enzalutamide

Among prostate cancer drugs, patients often encounter " enzalutamide and Enzalutamide ( Enzalutamide): two different ways of writing, and sometimes the trade name "Encotan" is also seen, so many people mistakenly think that they are different drugs. In fact, these names essentially refer to the same innovative drug, it is just a translation habit There are differences in naming methods. Enzalutamide is an international common name. Domestic literature and drug regulatory agencies usually use "enzalutamide" as the standard translation, while "enzalutamide" is another name formed based on spelling in the early days and can still be seen in some medical journals or materials. As for "Enzalutamide", it is a trade name jointly developed by Pfizer and Astellas Pharmaceuticals for commercial promotion in China and some markets.

Regardless of the name, the drug's ingredients, mechanism of action, and clinical application are exactly the same. They are all new-generation androgen receptor inhibitors, which mainly inhibit the proliferation of tumor cells by blocking the androgen receptor signaling pathway. Compared with first-generation anti-androgens, enzalutamide can interfere with the androgen pathway at a deeper level and is still effective in castration-resistant prostate cancer. It is applicable to both metastatic castration-resistant prostate cancer and is gradually being extended to patients with castration-sensitive stages.

Therefore, patients do not need to worry about the difference between "Enza" and "Enza" when choosing medicines.The two refer to the same medicine. The only thing that needs to be paid attention to is to identify the formal channels and the trade name "Acotan" during the drug purchase process to avoid purchasing drugs that are not standardized or from unknown sources due to name confusion. In academic research, clinical guidelines or medical insurance catalogs, it is also recommended to uniformly use "enzalutamide" as the standard translation to ensure the accuracy and consistency of medical information.

Reference materials:https://www.xtandi.com/