阿福他酶α的购买渠道有哪些？

Afotalase α is administered by subcutaneous injection, and its usage and dosage need to be individually adjusted according to the patient's age, weight and severity of the disease. Since the drug has not yet been officially approved for marketing in China, patients need to purchase it through overseas channels, including hospital pharmacies and online pharmacies. When purchasing, you need to pay attention to the storage conditions of the medicine (refrigerated at 2-8°C) and the quantity of medicine to prepare to ensure continuity of treatment.

What are the purchasing channels for aftase α?

It has not yet been officially launched in China. Patients need to obtain the drug through overseas channels. The following are some common purchasing methods.

Purchase in hospital pharmacies

In countries where aftase alpha is already on the market (such as the United States, Japan, and some European countries), patients can purchase it in hospital specialty pharmacies with a doctor's prescription. This method of medicine comes from regular sources and can be used under the guidance of a doctor, but the hospital inventory needs to be confirmed in advance.

Certified online pharmacies

Some nationally certified online pharmacy platforms can provide aftase alpha purchase services. Patients need to upload an electronic prescription and complete the purchase after review. This method is convenient and fast, and is especially suitable for patients with limited mobility, but it is necessary to carefully verify the platform qualifications to avoid purchasing counterfeit products.

Regular medical service institutions

Some qualified medical service institutions can provide purchasing services for aftase α. When choosing this channel to purchase drugs, you need to verify the platform qualifications to ensure the authenticity of the drugs.

No matter which purchasing channel is chosen, patients should keep complete drug purchase receipts and drug information for inspection. At the same time, attention should be paid to the storage conditions of drugs to avoid drug failure due to improper transportation.

The number of preparations for aftase α

Aftase α needs to be used for a long time, and patients need to plan the quantity of preparations reasonably to ensure the continuity of treatment.

Routine dosage calculation

The recommended dose is 6 mg/kg per week, divided into 3 or 6 subcutaneous injections. Taking the 18mg/0.45mL specification as an example, adult patients need 2-3 boxes per month. The specific dosage needs to be adjusted according to body weight and doctor's advice.

Drug Preparation Suggestions

Taking into account the validity period of the drug (usually 24 months) and transportation time, it is recommended that patients prepare enough for 3-6 months at a time. At the same time, a certain margin needs to be reserved to deal with emergencies (such as logistics delays or temporary dose adjustments).

When preparing medicine, ensure that the storage conditions meet the requirements (refrigerated at 2-8°C) to avoid drug failure due to improper storage. Check the expiration date of medicines regularly and avoid using expired medicines.

The medication course of aftase α

The medication course of aftase α needs to be adjusted according to the patient’s age, disease severity and treatment response, and is usually long-term maintenance treatment.

Perinatal/infancy-onset HPP

The recommended dose is 6 mg/kg per week, divided into 3 or 6 subcutaneous injections. If efficacy is insufficient (e.g., respiratory status, growth, or imaging findings do not improve), the dose may be increased to 9 mg/kg per week. Treatment needs to continue until bone development is stable, and some patients require lifelong medication.

Adolescent-onset HPP

The dosage is the same as in infancy, 6 mg/kg per week, divided into injections. The treatment goal is to improve bone mineralization and exercise capacity. The treatment course is usually long-term, and the efficacy and safety need to be regularly evaluated.

The use of aftase α must be done under the guidance of experienced medical professionals. Patients are not allowed to adjust the dosage or stop taking the drug on their own. During the treatment period, renal function, calcium and phosphorus metabolism indicators, and bone development need to be monitored regularly, and the treatment plan should be adjusted in a timely manner.