阿福他酶α一次能囤几盒?多少钱?

Afotalase α is an enzyme replacement therapy drug developed by Alexion Pharmaceuticals of the United States, with the trade name Strensiq. The drug is available in various strengths, including 18mg/0.45mL, 28mg/0.7mL, 40mg/mL and 80mg/0.8mL, among which the price of 18mg/0.45mL is approximately US$13,210. Since the drug needs to be used for a long time, patients often need to stock up on a certain amount, but storage conditions and expiration dates need to be considered. This article will introduce the drug in detail from three aspects: quantity, price information and contraindications.

How many boxes of aftase alpha can be stored at a time

It needs to be used for a long time. Patients usually need to store a certain amount of drugs to maintain treatment. The amount of drugs to be stored is affected by factors such as storage conditions, validity period, and financial ability.

Storage Condition Restrictions

Aphthase α needs to be stored refrigerated at 2-8°C, avoiding freezing or direct sunlight. Storage space in home refrigerators is limited, and it is usually recommended to store no more than 3 months' worth at a time to avoid improper storage that affects the effectiveness of the medicine.

Validity period and financial burden

The drug is usually valid for 24 months, and excessive hoarding may lead to expiration and waste. At the same time, aftase α is expensive, with 18 mg/0.45 mL being approximately US$13,210 per box. Stocking up on large quantities of the drug puts great financial pressure on patients.

Taking comprehensive consideration of storage conditions, validity period and economic factors, patients usually stock up on 1-3 months’ worth of medication at a time. The specific amount needs to be adjusted based on doctor’s advice and personal circumstances.

How much does aftase α cost?

The price of aftase α varies depending on the specifications, and it has not yet been officially approved for marketing in China. Patients usually need to purchase it through overseas channels.

18mg/0.45mL specification price

The price of 18mg/0.45mL/box of aftase α is approximately US$13,210, which is one of the commonly used clinical specifications. Adult patients usually require 2-3 boxes per month, and long-term treatment costs are higher.

Prices of other specifications

The prices of 28mg/0.7mL, 40mg/mL and 80mg/0.8mL specifications vary due to market fluctuations and regional differences. Due to the higher dosage, the price of a single box of 80mg/0.8mL is usually higher.

The high price of aftase alpha limits the accessibility for some patients, and the rare disease drug market is looking forward to more economical alternatives or medical insurance coverage policies in the future.

Contraindications of aftase α

As a biological agent, aftase α must strictly comply with the contraindications when using it to avoid serious adverse reactions.

Contraindicated in patients with allergies

Patients who are allergic to aftase α or its components are prohibited from using this drug. If severe allergic reactions occur (such as difficulty breathing, rash, etc.), you should stop taking the medicine immediately and seek medical advice.

Contraindicated during pregnancy and lactation

Currently there is insufficient data to support the safety of aftase alfa in pregnant and lactating women, so these two groups should avoid using this drug.

Contraindicated in patients with specific hereditary metabolic diseases

Patients with rare hereditary diseases such as galactose intolerance, total lactase deficiency or glucose-galactose malabsorption are contraindicated in patients with aftase α to avoid the risk of metabolic abnormalities.

The use of aftase alfa must strictly follow the contraindications, and patients should assess individual risks under the guidance of a doctor.