非布索坦医保吗？

It is a new and highly effective selective inhibitor of non-purine xanthine oxidase (a key enzyme that promotes uric acid production). Febuxostat is the latest XOR inhibitor developed in the world. It acts highly selectively on this oxidase to reduce the synthesis of uric acid in the body and lower the concentration of uric acid, thereby effectively treating gout.  

Among drugs that inhibit uric acid production, colchicine is mainly used in the acute phase of the disease. Compared with febuxostat, it is mainly allopurinol. Compared with allopurinol, febuxostat has less side effects and has the following advantages: 1. Allopurinol only inhibits reduced XOR, while febuxostat has a significant inhibitory effect on both oxidized and reduced XOR, so its effect of reducing uric acid is more powerful and lasting; 2. Since allopurinol is a purine analog, it will inevitably affect the activities of other enzymes involved in purine and pyridine metabolism. Therefore, repeated high-dose administration is required to maintain high drug levels during allopurinol treatment. This also leads to serious or even fatal adverse reactions due to drug accumulation. Febuxostat is a non-purine XOR inhibitor and therefore has a better safety profile.

Febuxostat can reduce the level of uric acid in the blood of gout patients with hyperuricemia. The dosage of Febuxostat is 40 mg or 80 mg once daily, but this product is not recommended for gout patients without hyperuricemia. The State Food and Drug Administration of China issued a new drug certificate for Febuxostat tablets to Jiangsu Wanbang Biochemical Pharmaceutical Co., Ltd. on June 26, 2013. The approved tablets are 40mg×16 tablets/box and 80mg×6 tablets/box. On June 26, 2013, the imported original drug Febuxostat was officially launched in China. It has been included in the National Medical Insurance (2019 version), numbered 911, the drug name is febuxostat, the dosage form is oral sustained-release dosage form, the drug category is musculo-skeletal system drugs > anti-gout drugs (XM>