defiteli多少钱一盒?
(Defibrinoside) has anti-thrombotic, fibrinolytic, anti-ischemic, and anti-infective effects in vivo and in vitro. Defiteli was approved for marketing in the European Union in October 2013, and was approved for marketing in the United States by the U.S. Food and Drug Administration (FDA) on March 30, 2016. It is suitable for the treatment of adults and children with hepatic veno-occlusive disease (VOD), also known as sinusoidal obstruction syndrome (SOS), and renal or pulmonary dysfunction after hematopoietic stem cell transplantation (HSCT).
Hepatic veno-occlusive disease (HVOD), also known as sinusoidal obstruction syndrome (SOS), is one of the serious complications after hematopoietic stem cell transplantation (HSCT), which mostly occurs within 30 days after HSCT. The incidence of HVOD after HSCT is approximately 8%-14%, and can reach 60% in high-risk patients.
In clinical trials, while heparin was used to prevent diseases such as hepatic veno-occlusion, it greatly increased the risk of bleeding. However, defiteli defibrotide, used alone or in combination with heparin, had a very low incidence of side effects and achieved good results in preventing HVOD. In a phase III multi-center randomized clinical trial completed in Europe, a total of 356 stem cell transplant patients were recruited. The incidence of hepatic vein occlusion 30 days after transplantation was compared. It was found that 2 of 180 patients in the defiteli (defibrinoside) group developed hepatic vein occlusion, accounting for 12%; 35 of 176 patients in the control group developed hepatic vein occlusion, accounting for 20%. The incidence rate of the disease was significantly reduced, and the effect was obvious.
The effect of defiteli is remarkable, and patients cannot help but want to know its price. The current price of defiteli on the market is around 22,000$, which may fluctuate due to factors such as exchange rates. For specific prices, please consult the medical companion and travel service.
The above is the price introduction. If you have other related questions, you can also consult the medical companion passenger service for answers.
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