去纤苷正品有合适的购买方式吗?
Introduction: On March 30, 2016, the U.S. Food and Drug Administration (FDA) approved defibrotide for the treatment of hepatic VOD in adults and children with renal or pulmonary dysfunction after HSCT. Defibrotide is the first FDA-approved therapy for the treatment of patients with severe hepatic VOD, and although its mechanism of action is not fully understood, defibrinoate sodium has been shown to enhance the enzymatic activity of plasmin, thereby hydrolyzing fibrin clots.
Defibrinoside increases the expression of tissue plasminogen activator and thrombomodulin and reduces the expression of von Willebrand factor and plasminogen activator inhibitor-1 in endothelial cells, thereby reducing endothelial cell activation and increasing endothelial cell-mediated fibrinolysis.
The appropriate way to purchase genuine defibrotide
1. Hospital pharmacies: In countries where defibrotide is listed, many hospital pharmacies will supply it, and patients can purchase it directly from the hospital pharmacy with a doctor's prescription.
2. Physical pharmacies: Some professional pharmacies or chain pharmacies may provide defibrotide sales services. You can purchase defibrotide from local pharmacies in the countries where defibrotide is listed.
3. Online pharmacies: There are some legitimate online pharmacies that may provide defibrinoside purchasing services. You can consult their customer service staff to learn more.
4. Drug suppliers: Some drug suppliers may sell defibrotide, and patients can learn about the purchasing process, price and other information by contacting the supplier.
The price of genuine defibrotide
Genuine defibrotide is developed and produced by JAZZ Pharmaceuticals. It is an original research drug. The price of a box is about 38,500$, which is relatively expensive. As a drug used to treat specific diseases, the genuine price of defibrotide varies due to various factors such as exchange rate fluctuations, regions, market supply and demand, etc. It is recommended to understand the price in various aspects before purchasing.
The above mentioned is for reference only. When purchasing, please refer to the quotation from local pharmacies or medical institutions. Patients can consult professional pharmaceutical consulting services to obtain the latest price information before purchasing. At the same time, you should make sure to choose formal channels when purchasing to ensure the genuine quality of the drugs.
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