恩瑞格的注意事项

The chemical name of Deferasirox () is 4-[3,5-bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid. It is an iron chelator product developed by the Swiss pharmaceutical company Novartis. It is the first oral iron anthelmintic approved by the US FDA for routine use. It is approved for use in patients ≥2 years old with chronic iron overload caused by blood transfusion. In Europe, it is recommended as a 6 As a first-line drug for patients with thalassemia and iron overload over the age of 18, Enrego is highly selective for iron (Fe3+). It is a ligand with 3 protrusions that binds iron with high affinity in a 2:1 ratio.

What are the precautions for Enrig?

1. Deferasirox may cause rash. Generally, the rash will disappear automatically without the need to adjust the dose or stop the medication. If the condition is serious or persistent, the medication should be stopped.

The patient's vision or hearing may be affected.

3. It should be taken 30 minutes before meals.

4. It should be taken at the same time every day.

5. Pregnant and lactating women: use with caution.

6. Medication for children: Children under 6 years old should use Enrige with caution. Not suitable for use by children under 2 years old.

7. Medication for the elderly: Use with caution.

When using Deferasirox (Enrig), please note that Deferasirox (Enrig) should be taken on an empty stomach at least 30 minutes before meals, once a day, preferably at the same time every day. Tablets should not be chewed or swallowed whole. Deferasirox (Enreg) should not be taken with aluminum-containing antacids, and the dose (mg/kg) needs to be calculated and rounded to the nearest whole tablet. Completely dissolve the tablets in water, apple juice or orange juice (100-200mL) by stirring until a clear suspension is obtained and then drink it. The remaining medicine must be added with a small amount of water, apple juice or orange juice and mixed well before taking. Not recommended for dissolution in carbonated drinks or milk as it can cause foaming and slow dispersion. You should strictly follow the doctor's instructions when taking it to avoid unnecessary complications.