恩瑞格怎么买？

Thalassemia is a relatively rare disease in life, but there are still some people who will suffer from this disease. Thalassemia is difficult to treat. Deferasirox () is an oral active chelating agent. It is used for patients with iron accumulation due to long-term blood transfusion (such as thalassemia or other rare anemias). It is suitable for children over two years old and adults.

How to buy Enrig?

Enrego is an oral active chelating agent that is highly selective for iron. Enrig is a ligand with three protrusions that binds iron with high affinity in a 2:1 ratio. Although deferasirox has a very low affinity for zinc and copper, the concentrations of these trace metals in the serum still decrease to varying degrees after administration. Therefore, Enriga can be mainly used to treat chronic iron overload caused by frequent blood transfusions in patients with β-thalassemia older than 6 years old.

At present, Enrig has been approved for marketing in China. Domestic patients can obtain deferasirox at large hospitals in my country with a prescription. The domestic price of Enrig is relatively high, with a box of approximately $2,000. It is recommended that patients with iron accumulation, such as those who require long-term blood transfusions, should take the drug according to their own weight. Generally, it is recommended to take 20 mg/kg daily at the initial stage. Next, it can be adjusted according to the serum ferritin index. The patient may need to adjust or increase the dose of deferasirox. Generally, the dose will be increased in units of 5 mg/kg or 10 mg/kg. The total dose of Enriga should not exceed 30 mg/kg per day. Patients need to pay about $24,000 a month.

If patients cannot afford the domestic price, they can consult overseas medical service organizations (such as Medical Companion Travel) to purchase Enrige, which is available in India. The original version of deferasirox produced by Novartis in India is 400mg*30 tablets/box, priced at approximately RMB 700; while the generic version of deferasirox produced by Cipla Pharmaceuticals in India is 500mg*30 tablets/box, priced at approximately RMB 500.