地拉罗司要注意什么？

The chemical name is 4-[3,5-bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid. It is an iron chelator product developed by the Swiss pharmaceutical company Novartis. It is the first oral iron-removing agent approved by the US FDA for routine use. It is approved for use in patients ≥2 years old with chronic iron overload caused by blood transfusion. In Europe, it is recommended as a first-line drug for patients with thalassemia iron overload over 6 years old. Enrig is highly selective for iron (Fe3+). It is a ligand with 3 protrusions that binds iron with high affinity in a 2:1 ratio.

Usage and dosage of Enriga: It is recommended for patients with iron accumulation, such as those who require long-term blood transfusion (blood transfusion volume up to 100 ml/kg) and whose serum ferritin exceeds 1000 μg/L. According to the body weight, it is initially recommended to take a daily dose of 20 mg/kg of deferasirox. Depending on the serum ferritin index, the patient may need to adjust or increase the dose of deferasirox, which is usually 5 mg/kg or 10 mg/kg. The dose is adjusted in units of kilograms, but the total dose should not exceed 30 mg/kg per day.

When we use drugs to treat diseases, we not only need to clearly understand the usage and dosage of the drug, but also need to accurately grasp the precautions during medication. So what should we pay attention to when taking deferasirox?

Precautions for deferasirox: First, deferasirox, the main ingredient of Enriga, may cause rashes. Although the rash usually disappears automatically without the need to adjust the dose or stop the medication, there are some patients whose condition is more serious or will continue to occur, so the medication must be stopped in time. Second, after taking this medicine, the patient's vision or hearing may be affected. Third, this medicine should be taken 30 minutes before meals. Fourth, the time of taking this medicine must be the same every day, so that the effect of the medicine will be better. Patients and friends should pay more attention to these precautions.

The treatment effect for thalassemia is good, and it can help everyone effectively reduce the harm of the disease. To learn more about deferasirox, you can contact Medical Companion Travel.