地拉罗司医保能给报销吗？

It is used to treat chronic iron overload caused by frequent blood transfusions (monthly administration of concentrated red blood cells ≥7 mL/kg) in patients with β-thalassemia older than 6 years old.

In 2010, deferasirox dispersible tablets were approved for marketing in China. So, can deferasirox be reimbursed by medical insurance?

According to Medical Companion Travel, deferasirox has not been officially included in medical insurance and is a drug paid for by patients at their own expense!

After deferasirox was launched on the market, the price in China was relatively high, with a box costing about $2,000. For an ordinary person weighing 60kg, the cost of taking deferasirox for a month exceeds about $24,000. It can be seen that it is difficult for ordinary families to accept this price.

Fortunately, Novartis of Switzerland imported deferasirox to India, with a specification of 400mg*30 tablets/box and a price of about $700.

The specification of Deferasirox produced by Indian pharmaceutical factory is 500*30 tablets/box, and the price is about 500$. Due to the fluctuation of exchange rate, the price will be different. Please consult the medical companion for the specific price! 

Patients can choose to purchase different versions of deferasirox according to their own conditions!

In addition, the recommended dose of deferasirox is 20 mg/kg.

For patients who receive monthly transfusions of more than 14 mL/kg of packed red blood cells (ie, more than 4 units/month in adults) and who need to reduce excess iron exposure, a starting dose of 30 mg/kg/day may be considered.

For patients who receive monthly transfusions of less than 7 mL/kg of packed red blood cells (i.e., less than 2 units/month in adults) and who need to maintain body iron balance, a starting dose of 10 mg/kg/day may be considered.

Overdose of deferasirox:

1. Cases of overdose (taking 2-3 times the prescribed dose for several weeks) have been reported. One case report reported that an overdose resulted in subclinical hepatitis, which resolved after discontinuation of the drug, with no long-term effects.

2. Thalassemia patients with iron overload can tolerate a single dose of 80 mg/kg with only mild nausea and diarrhea.

3. A single dose of 40mg/kg can be well tolerated by healthy volunteers.

4. Signs of acute overdose include nausea, vomiting, headache and diarrhea. Treatment of overdose includes induction of vomiting, gastric lavage, and symptomatic treatment.