恩瑞格如何使用呢？

It is used to treat chronic iron overload in patients with beta-thalassemia older than 6 years old due to frequent blood transfusions (monthly administration of concentrated red blood cells ≥7mL/kg); for children under 6 years old and iron overload caused by other transfusion-dependent diseases; then, how to use Enrig?

How to use Enrig: The common starting dose is 20 mg/(kg·d). If there is a large amount of blood transfusion and the iron increase is >0.5 mg/(kg·d) or the iron load before treatment is high, the recommended dose is 30 mg/(kg·d). If the iron increase is <0.3 mg/kg, 10-15 mg/kg/d is enough to control the condition.

Administer on an empty stomach 30 minutes before meals and should be completely dissolved in water or apple or orange juice.

It is not recommended to dissolve Enrige in carbonated drinks and milk, because it will cause foam and delay the dispersion speed; do not take it when the properties of the drug have changed; please use this product under the guidance of a physician; drug interactions may occur if used with other drugs at the same time, please consult a physician or pharmacist for details.

Lower doses of Enriga [5-10mg/(kg·d)] can only be used for young patients with mild iron overload and few blood transfusions, or elderly patients who have not received satisfactory results from chelation therapy in the past;

Patients taking deferasole 20 and 30 mg/(kg·d) need to carefully monitor body iron stores, because body iron levels may continue to rise in 50% and 10% of patients.

In addition, the frequency of blood transfusion can also affect the effect of Enriga in controlling liver concentration. When the iron intake is greater than 0.5mg/(kg·d), only 47% of patients who receive the same dose of Enriga have a reduction in liver concentration.

Enrige generally requires several courses of treatment:

There is no unified answer to the question of how many courses of treatment should be used, because each patient's condition and physical condition are different. Some patients have better physical constitution and milder conditions. Enrig's treatment is easier to work in the patient's body and heals faster. Generally, one or two courses of treatment is enough, while patients with poor physical fitness or severe illness need to use it for a longer period of time to be effective.