恩瑞格该如何使用呢？

On January 23, 2013, the FDA approved a new indication for the treatment of chronic iron overload in patients with non-transfusion-dependent thalassemia (NTDT) aged 10 years and above. So, how should Enriga be used?

The usage and dosage of Enrige is: recommended for patients with iron accumulation, such as those who require long-term blood transfusion (blood transfusion volume reaches 100 ml/kg) and whose serum ferritin exceeds 1000 μg/L; corresponding to body weight.

In the early stage of taking Enriga: It is recommended to take 20 mg/kg of Enriga daily. Depending on the improvement of serum ferritin indicators, patients may need to adjust or increase the dosage of Enriga. Generally, the dose will be increased in units of 5 mg/kg or 10 mg/kg, but the total dose should not exceed 30 mg/kg per day.

How to use Enrig:

Enriga should be taken once a day on an empty stomach, at least 30 minutes before a meal, preferably at the same time each day. Tablets should not be chewed or swallowed whole.  

Enriga should not be taken with aluminum-containing antacids, and the dose (mg/kg) needs to be calculated and rounded to the nearest whole tablet. 

Completely dissolve the tablets in water, apple juice or orange juice (100-200mL) by stirring until a clear suspension is obtained and then drink it. The remaining medicine must be added with a small amount of water, apple juice or orange juice and mixed well before being taken. Not recommended for dissolution in carbonated drinks or milk as it can cause foaming and slow dispersion.

Special groups of people taking Enrige:

1. Enrige should be used with caution for pregnant women, children under 6 years old, the elderly, and women during pregnancy;

2. Enrige is not suitable for use by children under 2 years old;

3. People who are allergic to Enrig and related ingredients are prohibited from taking this product.

The more common side effects include diarrhea, vomiting, headache, abdominal pain, fever, rash, increased serum creatinine, etc.; in addition, increased liver enzymes, cough, throat inflammation, and urticaria.