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(Enrig) is currently the only oral iron chelator developed by Novartis. It was approved by the FDA in November 2005 for use in patients 2 years and older with chronic iron overload caused by blood transfusions. Let’s take a look at the price of Deferasirox (Enrega) in India.

Deferasirox (Enrego) from Novartis, Switzerland, has a specification of 400mg*30 tablets/box, and the price is about $700. The specification of Deferasirox (Enrego) in India is 500*30 tablets/box, and the price is about $500. Due to exchange rate fluctuations, prices are uncertain. Please consult Medical Travel for specific prices. Patients in need can obtain drugs through domestic professional overseas medical service organizations (such as Medical Companion Travel).

The indications of Deferasirox (Enrige) are: 1. Patients with chronic iron overload transfusion hemosiderinosis secondary to blood transfusion who are 2 years old or older will have symptoms of chronic iron overload when serum ferritin continues to be >1000 L, and iron chelation therapy should be started at this time. 2. Iron chelators can also be given to patients undergoing ASCT treatment when iron overload occurs; 3. It can be used to treat reversible renal insufficiency caused by Fanconi syndrome.

Deferasirox (Enrige) is a tridentate iron chelator that combines with ferric iron ions in a 2:1 ratio to form a complex that is excreted in the feces, thereby reducing iron storage in the body. Due to the continued presence of Deferasirox in the plasma, plasma non-transferrin-bound iron can be continuously reduced and the iron formed by toxicity in the body can be directly eliminated. (Enrig) ​​is a drug approved to reduce iron burden, with a recommended starting daily dose of 20 mg/kg. For patients who receive monthly transfusions of more than 14 mL/kg of packed red blood cells (ie, more than 4 units/month in adults) and who need to reduce excess iron exposure, a starting dose of 30 mg/kg/day may be considered. For patients who receive monthly transfusions of less than 7 mL/kg of packed red blood cells (i.e., less than 2 units/month in adults) and who need to maintain body iron balance, a starting dose of 10 mg/kg/day may be considered. In patients who have already responded well to deferoxamine therapy, an initial dose equivalent to half the deferoxamine dose may be considered. Take it on an empty stomach at least 30 minutes before meals, once a day, preferably at the same time every day.

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