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(Enrig) is used for patients with iron accumulation due to long-term blood transfusion (such as thalassemia or other rare anemias). It is suitable for children over two years old and adults.

How to take Deferasirox (Enrige):

After receiving 10 to 20 blood transfusions. The common dose of deferasirox (Enrige) is 20 mg/(kg·d); if the child has a high iron load, the dose is 30 mg/(kg·d); if the child has a low iron load, the dose is 10 to 15 mg/(kg·d). A foreign prospective controlled study. Comparing the treatment of 296 children with thalassemia major taking deferasirox (Enrige) and 290 cases of deferoxamine.

It was found that oral administration of deferasirox (Enreg) at a dose of 20 mg/kg·d) could maintain serum ferritin at 2000ug/L; for example, oral administration of deferasirox (Enreg) at a dose of 30 mg/(kg·d) resulted in an average annual decrease in serum ferritin of 1249ug/L. LIC was applied to analyze iron loading status. It was found that oral deferasirox 20 mg/(kg·d) can effectively achieve iron balance in the body, while the dose of 30 mg/(kg·d) can achieve the purpose of reducing iron accumulation in the body, while the dose of 10 mg/(kg·d) is not enough to reduce iron accumulation in the body and causes a slow increase in iron accumulation.

Children over 2 years old, take once daily before meals.

Deferasirox should be taken once daily on an empty stomach, at least 30 minutes before a meal, preferably at the same time each day. Tablets should not be chewed or swallowed whole. Deferasirox (Enreg) should not be taken with aluminum-containing antacids, and the dose (mg/kg) to be administered needs to be calculated and rounded to the nearest whole tablet.

Completely dissolve (Enrige) in water, apple juice or orange juice (100-200mL) by stirring until a clear suspension is obtained and then drink it. The remaining drug must be added with a small amount of water, apple juice or orange juice and mixed well before taking it. Not recommended for dissolution in carbonated drinks or milk as it can cause foaming and slow dispersion.

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