恩瑞格（地拉罗司）多少钱一盒？

(Deferasirox) is currently the only oral iron chelator. It was approved by the FDA in November 2005 for use in patients 2 years and older with chronic iron overload caused by blood transfusions. Compared with deferoxamine, Enrig is more convenient and has higher patient compliance. Today let’s take a closer look at how much a box of Enrig (Enrig) ​​costs?

In 2010, Enrig (deferasirox) was approved for marketing in China. According to Medical Partner Travel, Enrig (deferasirox) has not been officially included in medical insurance. Enrig India Cipla Desirox 500mg*30 tablets is about 240$. Swiss Novartis Asunra 400mg*30 tablets is around 420$. Patients in need can purchase drugs abroad or obtain drugs through domestic professional overseas medical service organizations (such as Medical Companion Travel), which are guaranteed to be genuine.

Iron overload increases the risk of infection, endocrine system damage, vital organ dysfunction, AML transformation in MDS patients, and shortens survival. Iron chelators are currently the mainstream treatment for iron removal. Among them, Enrig (deferasirox) is easy to administer, significantly reduces ferritin levels, and has a definite effect in protecting important target organ systems such as the liver, heart, and endocrine system. It is currently the preferred option for iron removal treatment.

Enrig (deferasirox) is a drug approved to reduce iron burden, with a recommended starting daily dose of 20 mg/kg. For patients who receive monthly transfusions of more than 14 mL/kg of packed red blood cells (ie, more than 4 units/month in adults) and who need to reduce excess iron exposure, a starting dose of 30 mg/kg/day may be considered. For patients who receive monthly transfusions of less than 7 mL/kg of packed red blood cells (i.e., less than 2 units/month in adults) and who need to maintain body iron balance, a starting dose of 10 mg/kg/day may be considered. In patients who have already responded well to deferoxamine therapy, an initial dose equivalent to half the deferoxamine dose may be considered. Take it on an empty stomach at least 30 minutes before meals, once a day, preferably at the same time every day.

Enrig (deferasirox) dispersible tablets are oral active chelating agents that are highly selective for iron (Fe3+). It is a ligand with 3 protrusions that binds iron with high affinity in a 2:1 ratio. Although Enriga has a very low affinity for zinc and copper, the concentrations of these trace metals in serum decreased to varying degrees after administration. The clinical significance of these reductions in metal concentrations is unclear. It should be noted that Enrig dispersible tablets should be used with caution in patients with reduced liver and kidney function, elderly patients, pregnant and lactating women, and children under 6 years old; children under 2 years old should not use it.

The above is the price content of (deferasirox), I hope it can help you!

Recommended related hot articles: /newsDetail/80957.html