瑞士诺华地拉罗司怎么购买？

Novartis is used for patients with iron accumulation due to long-term blood transfusion (such as thalassemia or other rare anemias). It is suitable for children over two years old and adults.

Clinical trials explore the efficacy and safety of the iron chelator deferasirox in the treatment of iron overload in children with β-thalassemia major (β-TM). The trial selected 24 children with β-TM iron overload who received regular blood transfusions to participate in the study to investigate the changes in serum ferritin (SF) and adverse reactions.

Results: The initial dose of deferasirox (Enrige) of 20-30 mg/kg per day had no obvious effect on children with iron overload. After the dose was increased to 30-40 mg/kg per day, the SF level dropped significantly (U=58); the most common adverse reaction was an increase in serum liver transaminases, followed by a non-progressive increase in serum creatinine. The SF level in the 5-year continuous deferasirox treatment group was significantly lower than that in the control group (1748±481 ng/mL vs 3462±1744 ng/mL); the liver MRI T2 value was significantly higher than that in the control group (8.5±2.9 ms vs 2.7±1.9 ms). There was no statistically significant difference in the mean cardiac MRI T2 values ​​between the two groups. Deferasirox (Enrige) can significantly reduce SF levels in children with β-TM, and shows dose-dependent changes; it does not show obvious advantages in reducing cardiac iron load, but has a significant effect in reducing liver iron load.

How to buy Novartis deferasirox in Switzerland?

It is a prescription drug. To purchase Novartis deferasirox from Switzerland, patients need a prescription from a professional doctor. It is recommended that you purchase it through formal channels. For details, you can consult the overseas medical service company Medical Travel.

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