瑞士诺华的地拉罗司药品说明书

[Drug Name], Enrige, Deferasirox, Desirox

[Indications] It is used to treat chronic iron overload in patients with β-thalassemia older than 6 years old due to frequent blood transfusions (monthly administration of concentrated red blood cells ≥ 7 mL/kg); for children under 6 years old and iron overload caused by other transfusion-dependent diseases.

[Usage and Dosage] Deferasirox should be taken on an empty stomach at least 30 minutes before meals, once a day, preferably at the same time every day. Tablets should not be chewed or swallowed whole. Deferasirox should not be taken with aluminum-containing antacids, and the dose (mg/kg) needs to be calculated and rounded to the nearest whole tablet. Completely dissolve the tablets in water, apple juice or orange juice (100-200mL) by stirring until a clear suspension is obtained and then drink it. The remaining medicine must be added with a small amount of water, apple juice or orange juice and mixed well before taking. Not recommended for dissolution in carbonated drinks or milk as it can cause foaming and slow dispersion.

[Side Effects] >10%: Increase in serum creatinine (dose related; 7-38%), abdominal pain (21-28%), nausea (11-23%), vomiting (10-21%), diarrhea (12-20%), proteinuria (19%), irritability (19%), headache (16%), cough (14%), nasopharyngitis (13%), sore throat (11%), influenza (11%), rash (8-11%).

[Precautions] Deferasirox may cause rash. Generally, the rash will disappear automatically without the need to adjust the dose or stop the medication. If the condition is serious or persistent, the medication should be stopped. The patient's vision or hearing may be affected. It should be taken 30 minutes before meals. It should be taken at the same time every day.

The above instructions are instructions. Please use the medicine correctly under the guidance of a doctor.

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Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.