诺华地拉罗司的用法用量
Novartis is used to treat chronic iron overload caused by frequent blood transfusions (monthly administration of concentrated red blood cells ≥ 7 mL/kg) in beta-thalassemia patients older than 6 years old. For iron overload caused by children under 6 years old and other transfusion-dependent diseases, Novartis deferasirox has limited safety and efficacy data in Chinese patients, and it is recommended to use it with caution based on the specific conditions of the patient.
Iron chelators can effectively increase iron excretion, reduce iron content in the body and its pathological deposition in various organs. Deferasirox is currently the only effective drug for the treatment of iron overload.
Novartis is a pharmaceutical and biotechnology multinational company headquartered in Basel, Switzerland. Its core businesses are in various patent medicines, consumer healthcare, generic medicines, eye care and animal health.
Novartis deferasirox dosage:
1. The recommended starting daily dose is 20mg/kg.
2. For patients who receive monthly transfusions of more than 14 mL/kg of packed red blood cells (ie, more than 4 units/month for adults) and need to reduce excess iron exposure, a starting dose of 30 mg/kg/day may be considered.
3. For patients who receive monthly transfusions of less than 7 mL/kg of packed red blood cells (i.e., less than 2 units/month for adults) and who need to maintain iron balance in the body, a starting dose of 10 mg/kg/day may be considered.
4. For patients who have responded well to deferoxamine treatment, an initial dose equivalent to half of the deferoxamine dose can be considered.
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