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Novartis is used for patients with iron accumulation due to long-term blood transfusion (such as thalassemia or other rare anemias). It is suitable for children over two years old and adults.

How to take Novartis deferasirox:

The recommended starting daily dose of deferasirox is 20 mg/kg.

For patients who receive monthly transfusions of more than 14 mL/kg of packed red blood cells (i.e., more than 4 units/month in adults) and who need to reduce excess iron exposure, a starting dose of 30 mg/kg/day may be considered.

For patients who receive monthly transfusions of less than 7 mL/kg of packed red blood cells (i.e., less than 2 units/month in adults) and who need to maintain body iron balance, a starting dose of 10 mg/kg/day may be considered.

In patients who have responded well to deferoxamine therapy, an initial dose of deferasirox equal to one-half the deferoxamine dose may be considered. (For example, a patient receiving deferoxamine 40 mg/kg/day 5 days per week or equivalent may start at 20 mg/kg if switched to deferasirox.)

Preparation:

Deferasirox should be taken once daily on an empty stomach, at least 30 minutes before a meal, at the same time each day. Tablets should not be chewed or swallowed whole. Deferasirox should not be taken with aluminum-containing antacids, and the dose (mg/kg) needs to be calculated and rounded to the nearest whole tablet.

Completely dissolve in water, apple juice or orange juice (100-200mL) by stirring until a clear suspension is obtained and then drink it. The remaining drug must be added with a small amount of water, apple juice or orange juice and mixed well before taking it. Not recommended for dissolution in carbonated drinks or milk as it can cause foaming and slow dispersion.

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Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.