地诺孕素的优势是什么？副作用大吗？

Ovarian endometriosis cyst removal is the main clinical treatment for ovarian endometriosis (OEM), but the risk of postoperative recurrence is high, and retreatment after recurrence is very important. Studies have shown that surgical treatment for patients with recurrence after OEM surgery can affect ovarian function, and patients with recurrence after OEM surgery should not undergo surgery again. Therefore, finding a safe and effective conservative therapy has important clinical significance. It is a mixed progestogen with very ideal pharmacological properties and no estrogenic anti-estrogenic and androgenic activity. It is the first-line option for OEM postoperative treatment recommended in Guideline 4. So, what are the advantages of dienogest? Are there any serious side effects?

The advantages of dienogest are reflected in three aspects. The first aspect is that it can treat pain and shrink lesions. Pelvic pain and dyspareunia are the main complaints of patients with endometriosis and are also the main focus of drug treatment. Dienogest can significantly improve dysmenorrhea and chronic pelvic pain; the second aspect is that dienogest can improve patients' fertility. The drug still has a good effect on recurrent endometriosis and avoids the damage to fertility caused by repeated surgical treatments. The third aspect is that dienogest can inhibit recurrence. A study included 203 patients with chocolate cysts, and they were given dienogest 2 mg/d after surgery and used continuously for 12 months. After an average follow-up of 30 months, only 3 patients relapsed, with a recurrence rate of only 1.5%, suggesting that dienogest can effectively prevent recurrence and avoid repeated surgical injuries. The above are the advantages of dienogest, but even such a drug has certain side effects.

: Irregular bleeding, amenorrhea, headache, depression, breast pain, breast swelling, chest discomfort, acne, etc. The side effects of dienogest are minor and most will recover after stopping the medication.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.