都2022年了你还不知道埃索美拉唑与奥美拉唑的区别吗？

Gastric ulcer is a common disease in the digestive tract system, mostly occurring in the stomach, duodenum, esophagus and other parts of the body. Omeprazole is a proton pump inhibitor that mainly targets some symptoms caused by excessive gastric acid secretion, such as ulcers, gastritis, reflux esophagitis and other diseases that cause abdominal distension, abdominal pain, acid reflux, etc. due to excessive gastric acidity. In addition, it also has a significant inhibitory effect on gastric acid secretion caused by stimulation of histamine drugs, gastrin, etc. It is clinically safer, more effective, and has less side effects. So, it’s 2022 and you still don’t know the difference between esomeprazole and omeprazole?

The difference between esomeprazole and omeprazole: 1. Esomeprazole is the S-isomer of omeprazole. Compared with the right-handed R-type omeprazole isomer, esomeprazole has a better effect of inhibiting gastric acid, while omeprazole belongs to the purified left-handed isomer configuration, and its metabolic pathways in the body are different. 2. Medicinal efficacy. Esomeprazole is a new generation product of omeprazole. It is very similar in terms of mechanism of action and clinical use range. However, esomeprazole has a stronger effect of inhibiting gastric acid. It is also less affected by the metabolism of genetic polymorphisms and has smaller side effects. It is a newer and better preparation for inhibiting gastric acid than omeprazole.

According to relevant studies, the total effective rate of esomeprazole is 97.18%, which is significantly higher than that of omeprazole (84.51%), and there is no significant difference in the incidence of adverse reactions. In the treatment of Helicobacter pylori-related gastric ulcer, compared with omeprazole, esomeprazole has more obvious therapeutic effect and higher safety. It can effectively relieve patients' gastrointestinal symptoms and promote patients' recovery, and is worthy of clinical promotion and application.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.