2025年那他珠单抗(Natalizumab)最新价格是多少钱一盒？

The drug price of Natalizumab is published overseas and is not used for domestic sales.

How much is the latest price of a box of Natalizumab in 2025?

Drug prices are greatly affected by countries/regions, medical insurance policies, procurement channels and specific brands, and change frequently.

The price of one box (300mg/15mL) is approximately US$3,400, which is only used as a reference for international market price conversion. The actual price in mainland China may be significantly different from this, and the final price depends on whether factors such as medical insurance, hospital purchase price, and drug brand are included.

The pictures are from public channels (such as the official website of the FDA, the official website of the original drug manufacturer, etc.) and are for reference only.

Natalizumab (Natalizumab) Medication for Special Populations

The use of Natalizumab in specific populations requires extreme caution, and it must be strictly evaluated by a doctor before the benefits outweigh the risks.

1. Pregnant women

Based on animal studies, this product may cause harm to the fetus. There have been postmarketing reports of thrombocytopenia (sometimes with anemia) in neonates exposed to natalizumab during pregnancy.

Before taking the drug, women of childbearing age should be informed of the potential risks of the drug to the fetus. If they become pregnant while taking the drug, they must inform their doctor immediately.

2. Lactating women

Natalizumab can be secreted into breast milk. However, its effects on breastfed infants and its impact on milk secretion are currently unknown.

The developmental and health benefits of breastfeeding to the baby, the mother’s clinical need for the drug, and the potential adverse effects of the drug or underlying maternal disease on the breastfed baby should be comprehensively considered, and doctors and patients should make a joint decision on whether to discontinue the drug or stop breastfeeding.

3. Elderly patients

Clinical studies have not included a sufficient number of patients aged 65 and above to determine whether their responses are different from younger patients.

4. Pediatric patients

The safety and effectiveness in pediatric patients under 18 years of age with multiple sclerosis or Crohn's disease have not been established.

Correct storage method of Natalizumab

1. Storage of unopened original solution

(1) Temperature: It must be refrigerated and stored in an environment of 2°C to 8°C (36°F to 46°F).

(2) Light protection: It needs to be stored away from light, usually in the original packaging box.

(3) Freezing and shaking are prohibited: Do not freeze or shake the original solution bottle violently, otherwise the biological activity of the drug may be destroyed.

(4) Expiration date: Be sure to use it before the expiration date marked on the drug packaging box and bottle label.

2. Storage and use of diluted solutions

(1) Immediate use: It is best to use the diluted solution immediately.

(2) Short-term refrigeration: If it cannot be used immediately, the diluent can be refrigerated at 2°C to 8°C.

(3) Usage time limit: The diluted solution must be infused within 4 hours.

(4) Warming up: If the diluent has been refrigerated, it should be taken out and allowed to rise to room temperature naturally before infusion.

(5) Observation: Before infusion, the diluent should be visually inspected for particles or discoloration. If so, it should not be used.